Vitamin D3 (Jarrow) Each bottle, 100 softgels. Each softgel, 1000 IUs of vitamin D3 (cholecalciferol).

Vitamin D3 is increasingly found to be important to sustain good health of not only bones, but other tissues such as the brain, intestines, muscle and immune function as well. Recent data suggest that higher amounts may be beneficial. Stay tuned for more information on the latest research!

Suggested use is one cap per day with meals. This is may help to supplement a multivitamin that has lower amounts of D3 (for example, the Ultra Preventive we carry only has 100 IUs).

Some recent research! Villamor E. A potential role for vitamin D on HIV infection? Nutr Rev. 2006 May;64(5 Pt 1):226-33

Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA. evillamo@hsph.harvard.edu

Despite advances in the knowledge of vitamin D's potent immunomodulatory activity, its role on HIV disease progression is unknown. Decreased concentrations of 1alpha,25-hydroxyvitamin D3, or 1,25(OH)2D, the active form of vitamin D, have been reported among HIV-infected people and attributed to defects in renal hydroxylation and increased utilization. A few studies also described low levels of 25-hydroxyvitamin D3, 25(OH)D, the vitamin obtained from solar synthesis and diet. An inverse association between 1,25(OH)2D concentrations and mortality has been reported from a small cohort of HIV-infected adults, and some cross-sectional studies have indicated positive correlations between 1,25(OH)2D and CD4+ cell counts. Additional observational studies are needed to confirm the associations between vitamin D status and HIV disease progression. These investigations would provide useful insights on the potential role of vitamin D supplementation to HIV-infected persons and the planning of intervention trials.